St. James is a census-designated place (CDP) in Washington County, Maryland, United States.

According to the United States Census Bureau, the CDP has a total area of 6.0 square miles (16 km2), all land.

As of the census[4] of 2000, there were 1,657 people, 631 households, and 499 families residing in the CDP.

There were 655 housing units at an average density of 109.4 per square mile (42.2/km2).

16.8% of all households were made up of individuals, and 9.0% had someone living alone who was 65 years of age or older.