In 1713, Charles Calvert, 3rd Baron Baltimore, gave 10,000 acres to his (fourth) wife Margaret, which ultimately became the My Lady's Manor historic district (in 1978).

Maryland's legislature confiscated the My Lady's Manor property during the American Revolutionary War and stored gunpowder in the church building (which remained standing).

However, construction of a road between Baltimore and York, Pennsylvania in 1803, and westward migration inhibited development in this specific area, which remained rural.

Construction of a 60x30 foot brick chapel, a Maryland vernacular interpretation of Georgian ecclesiastical architecture, was initially finished in 1755.

[4] A school was constructed adjacent to the church in 1821, but its buildings physically dismantled in 1884 and the bricks reused in the new bell tower.