St. John's Girls' Higher Secondary School is located in Nazareth, Tamil Nadu, India.

James Hough, also Chaplain of the East India Company, at Palamcottah, started a girls school at Nazareth in the year 1819, and in the year 1826, this school was closed due to financial constraints.

There are many Christian missionaries who have been stationed and worked at Nazareth, Tamil Nadu.

spoke kindly to the parents, offered gifts to them and stressed the need for female education.

Later, women missionaries like Anne Brotherton, and Harriet Strachan also took control of this school one after the other.

A chapel inside the school premises was built by the efforts of Rev.