After the 1921 season, the Giants were sold by African-American promoter Charlie Mills to Dick Kent and Dr. Sam Sheppard, who built a new park and renamed the club the Stars.
Led by a historic season by Charleston (the latest research shows him batting .436, with 12 home runs and a league-leading 32 stolen bases in 62 games), who was nearly matched by Blackwell (.430), and with Bill Drake contributing 16 wins, the Giants surged to second place with a 40–28 record.
An African-American industrial league team used the name in the late 1930s (it was also known as the St. Louis Titanium Giants), counting eventual major leaguer Luke Easter among its players.
The Stars inherited almost the entire roster of the 1921 Giants (who had finished in second place), with the exception of Hall of Fame center fielder Oscar Charleston.
Midway through the year, they acquired several players from the Toledo Tigers when that team folded, including new manager Candy Jim Taylor.
The next year, they won the second-half title with a 38–12 record after only narrowly losing the first half (69–27 overall) but lost the playoff series to Bullet Rogan and the Kansas City Monarchs.
They defeated the Chicago American Giants, second-half winners (and Negro league world champions for two years running) in an exciting playoff series, 5 games to 4.
The Stars continued their winning ways in 1929, but were just edged out in both halves of the season by the Kansas City Monarchs, despite Willie Wells's 27 home runs (tying Suttles's 1926 record).
Despite special rules that in some seasons counted home runs hit over the car barn as ground-rule doubles, the park proved very friendly to power hitters over the years.