The team was a member of the Central Division of the American Conference, in the Arena Football League (AFL).

The Stampede competed in the 1995 and 1996 seasons, playing their home games in the Kiel Center (since renamed the Enterprise Center), also the home of the St. Louis Blues of the National Hockey League.

The Stampede were coached by Earle Bruce during the 1995 season, and for the first 4 games of the 1996 season, before he announced his resignation to spend more time with his family.

Reaching the playoffs both seasons, they scored 49 points in two first-round games.

The following Stampede players were named to All-Arena Teams: Note: Statistics are correct through the end of the 1996 Arena Football League season.