St. Mary Church is a Catholic parish in Helena-West Helena, Arkansas, in the North Delta deanery of the Diocese of Little Rock.

In 1857, the Sisters of Charity of Nazareth arrived at the invitation of Bishop Byrne, who purchased 10 acres of land in Helena for them to build a convent and a Catholic school, which would become Sacred Heart Academy.

The school would move to a new building in 1918, but facing declining enrollment after World War II, it closed in 1968.

More importantly, a writeup of the church was published in Architectural Forum, which caught the attention of Eliel Saarinen.

Saarinen wrote a congratulatory letter to Eames and offered him a fellowship at Cranbrook Academy of Art to study architecture.