[5] St. Mary's is accredited by AdvancED, the Archdiocese of Baltimore, and is recognized and approved by the Maryland State Department of Education.

[3] The demographic breakdown of the 479 students enrolled in 2017-2018 was:[4] The school is located in downtown Annapolis on Duke of Gloucester Street.

Originally, the School Sisters of Notre Dame maintained a convent on the property; that building has since been transformed primarily into a library and computer labs.

Being located in a dense, urban area and surrounded by historic properties, the school does not have athletic fields of its own on campus.

[6] The school newspaper is The Crabnet, and St. Mary's has a total of 25 clubs, including a sailing team, Model UN, and a variety of others.