The local chieftain of "Mangattu", also referred to as "Mangattachan", graciously welcomed Christians into the area and granted them many privileges including the right to establish a church, a market and a town in 'Anke malee' (later Angamaly).

The number of Christians in Angamali swelled with further migrations, perhaps predominantly following the great flood in Periyar in 1341 that stilted the waters of the Muziris port.

This incident is documented in King Keshava Rama Varma of Cochin's letter to Pope Gregory XIII, written on 2 January 1576 to express his concern over the Roman Catholic missionaries' misconduct to the then Metropolitan Abraham: The Archdeacon George, likewise Our subject, has recently erected a church under the title of the Assumption of Our Lady in August, for which he requests me to obtain from Your Holiness certain Indulgences, which if granted, I shall regard as a favour done to me.

[12]Antonio de Gouvea, in his book Jornada do Arcebispo de Goa Dom Frey Aleixo de Meneses (1606), the travelogue of Alexis de Menezes the padroado Archbishop of Goa who convened the Synod of Diamper, gives an account of the churches in Angamaly: Angamalle (Angamali) has three big churches, the Cathedral had been dedicated to Hermusio (Hormusio) Abbot, a Nestorian heretic, and very important head of this heresy; the Archbishop changed its name to Saint Hormisda, martyr of Persia, which is the same name in the Malabar language, and persuaded the people that that was the Patron Saint of that church, that they were mistaken about the day and the legend of his life, and he ordered the burning of the book on the life of the said Hormusio, for having many errors and heresies, which he first showed to all the Cassanars, which they confessed to be so.Following the Synod of Diamper and Coonan Cross Oath, the community underwent a schism into Syrian Catholic and Jacobite factions.

[4] In 1566, Chaldean Patriarch Abdisho IV Maron gave his accent to the election and appointed George of Christ as the bishop of Palur and coadjutor of the Archdiocese of Angamaly to ensure a successor to Metropolitan Abraham.

The Catholic historian Bernard Thoma Alencherry records that the Syrian Christians in Mangad, Kochi, Purakad, and Thekkumkur who were loyal to Archdeacon George of Cross were threatened by local kings and Petty chieftains to attend the Synod of Diamper in 1599, as commanded by the Portuguese.

[4] After the Coonan Cross Oath of 1653, a delegate of the Syriac Orthodox Patriarch of Antioch, Gregorios Abdal Jaleel an archbishop of Jerusalem, arrived in Malabar.

After the Synod of Diamper and Coonan Cross Oath, which lead to the schism among the Saint Thomas Christians, the Angamaly Cheriyapally came under the control of the Jacobite faction, who were known by then as the Puthenkoor.

This Syriac Bible might have been brought to India by Fathers from the Holy See of Antioch as in its appendix you can see intercessory prayers to St. Mary and Mar Severios.