St. Mary, Star of the Sea is a Roman Catholic Church in the Federal Hill South neighborhood of Baltimore, Maryland.

The church venerates Stella Maris, Our Lady, Star of the Sea, and carries a beacon atop its spire to welcome sailors to the Port of Baltimore.

A direct passenger rout ran by Norddeutscher Lloyd between Bremen to Port Covington on the south end of the peninsula became a big source of population influx.

The first stage of construction of the new church was completed by 1871, and was fully funded by local festivals and street harvest markets.

After the construction of the church's spire, a glass star illuminated by candles was placed at the top, as a beacon visible from ships entering the port to welcome home Irish sailors.