St. Michael's Mission is an Episcopal church mission established about 1887 in Fremont County, Wyoming to minister to the Arapaho and Shoshone of the Wind River Indian Reservation.

It was founded by Reverend John Roberts with the permission of Shoshone Chief Washakie.

In 1900 a small log church was built about 3 miles (4.8 km) from the present location.

In 1910 the mission received an endowment from Mrs. Baird Cooper and the new site was developed over the next seven years.

The log church is accompanied by several frame buildings including a former schoolhouse, residences and a cultural center.