It is noted for its murals by Maxo Vanka,[3] painted in 1937 and 1941, such as Immigrant Mother Raises Her Sons for American Industry[4] and The Capitalist.

In 2019 it was reorganized as a personal (non-territorial) parish within the Shrines of Pittsburgh, a grouping of six churches with unique histories which the diocese hoped to promote as pilgrimage and visitor destinations.

Seeking an artist who would understand the cultural background of the parish, he approached the well connected Slovene-American writer Louis Adamic, who recommended his friend Maksimilijan "Maxo" Vanka.

Vanka, a former professor at the Academy of Fine Arts, University of Zagreb, had struggled to find work since immigrating to the United States and happily accepted the commission to create murals for the church.

During this time, he became convinced that the church was haunted by a ghostly, black-robed figure, which Adamic later wrote about in a piece for Harper's Magazine titled The Millvale Apparition.

[18] With World War II then raging in Europe, these murals featured much more overtly anti-war subject matter than the earlier ones.

The subject matter of the murals includes a combination of traditional religious imagery and social themes related to the Croatian American experience, such as war, injustice, and exploitation of workers.