It was built in 1881 from local Fall River granite, and added to the National Register of Historic Places in 1983.

[2] In 2002, the church was part of a three-parish merger between St. Patrick's, Blessed Sacrament, and Our Lady of the Angels.

In 2018, it became part of the Catholic Community of Central Fall River, a collaborative of parishes that includes Good Shepherd, the Cathedral of St. Mary of the Assumption, and St. Stanislaus Parish and School.

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