St. Paul's Cathedral (Spanish: Catedral de San Pablo) is a historic Anglican church in Valparaíso, Chile.

St. Paul's began in 1837 as a house church serving the British expatriate community in the cosmopolitan port city of Valparaíso, with divine services conducted by traveling Anglican chaplains.

[1] At the time and until 1865, Chilean law restricted all faiths but Catholicism, but in 1857—amid the growing influence and wealth of the British expat population—Anglicans were permitted to build a church in Cerro Concepción.

The service was presided over by Samuel Morrison, the Anglican bishop of Valparaíso, and attended by Louise de Souza, the British ambassador to Chile.

[3] The building's interior, whose present-day appearance dates to 1883,[1] has a long single nave illuminated with lancet windows; the roof is supported by exposed wooden trusses.