St. Paul's College, Kalamassery located at Kochi was founded by Joseph Attipetty, the late Archbishop of Verapoly to commemorate the historic visit of Pope Paul VI to India in connection with the 38th International Eucharistic Congress held in November - December 1964.
The foundation stone of the college was blessed by the pope on 3 December 1964 and was solemnly laid by Samuel Mathai, the Vice-Chancellor of the University of Kerala in the presence of Joseph Attipetty on 13 February 1965.
The college started functioning from 13 July 1965 imparting instruction to students for the two year pre-degree course.
At present the college offers postgraduate courses in economics, physics, mathematics, chemistry, commerce and English.
A change in the academic and infrastructural domains accredited the college ‘A’ grade in the cycle of re-accreditation by NAAC in 2016.