Its distinctive Carpenter Gothic Victorian style makes it a signature building for the downtown area.

The church is located just three blocks south of University Avenue.

At the corner of Waverley and Homer Avenues, it's at the northern edge of the historic Professorville neighborhood of the city.

The church was used as a location in the Hal Ashby film Harold and Maude (1971).

St. Aloysius was closed in 1994, the Newman Center at Stanford was reestablished as St. Dominic Parish in 1997, and St. Ann was sold in 1999.