St Brendan's is a state funded sixth form college located in Brislington, Bristol, England.

St Brendan's was founded by the Irish Christian Brothers as a Catholic school for boys in 1896 in Berkeley Square in Bristol.

Following the Education Act 1944, Saint Brendan's became a boys' direct grant grammar school and by the late 1950s had outgrown the Berkeley Square site.

[1] Its reputation and the breadth of subjects and courses now offered draw many students from secondary schools across Bristol, Bath and South Gloucestershire.

In May 2009, the group won the National Union of Students LGBT Campaign award "FE Society of the Year".