The church building, designed by Sir Edward Maufe, is located in Pont Street, Knightsbridge, near Harrods department store.

A congregation was established near what is now Trafalgar Square, with a permanent church later being built in Crown Court near Covent Garden.

The original St Columba's Church building of 1884 was destroyed by wartime bombing during the night of 10 May 1941.

[5] The current minister (as at April 2020) is the Rev C. Angus MacLeod, who was inducted to the charge by the Church of Scotland's Presbytery of England on 7 June 2012.

There have been three Ministers of St. Columba's who have held the office as Moderator of the General Assembly of the Church of Scotland: