Mother Rose Niland took possession of the buildings on behalf of the Dominican Sisters of Newcastle on 21 June 1923 and on the 31st of July that year the first 28 boarders arrived.
With an enrollment of 60 pupils St. Dominic's Convent School was officially opened and registered with the Transvaal Education Department on 1 August 1923.
The 1923 Mayor of Boksburg, Councillor Campbell, described St. Dominic's as a magnificent building where students should find studying a pleasure under ideal conditions.
[citation needed] Sports available include swimming, water polo, tennis, squash, volleyball, netball, field hockey, soccer and drum majorettes.
As multiple national winners, the senior team has competed overseas and most of the girls achieved Springbok colours, where they represented their country in World championships.