[2] Archbishop Enos Nuttall is considered to be the founding father of St. Hugh's High School.

The Deaconesses were involved in education and in 1897 the Cathedral High School for Girls was founded in Spanish Town.

St Hugh's College, Oxford, England, was the alma mater of Miss Evelyn Stopford who became principal in 1926.

The school's colours of blue and gold were chosen as well as the swan as the emblem and fidelitas as the motto.

Bishop William Hardie was instrumental in procuring the land as a permanent home for St Hugh's High School.

In 1948, a new block of buildings was formally opened, housing a library, an art room and science laboratory, and additional classrooms were added in 1949.

A Commercial Department was opened in 1965 and in the late 1960s a modern language laboratory was built, along with a swimming pool.

A Development Fund campaign, chaired by Mr Aaron Matalon, was launched in April 1967, with the aim of raising £100,000 over three years.

The school acquired the Aub house and also secured permission to use a portion of the Caenwood property for a playing field.

As of the 2018–2019 academic year, there were 1,375 students enrolled with a staff complement of seventy-eight (78) teachers, including two guidance counselors and a school nurse.