The town is located in the Shire of Moira local government area, 238 kilometres (148 mi) north of the state capital, Melbourne.

[1] The town of St James came into being as a result of selectors taking up land in the district.

The first selection of land in the St James area was thought to be in 1870.

St James Post Office opened on 10 July 1899.

[5] Media related to St James, Victoria at Wikimedia Commons This article about a location in Hume (region) is a stub.