The institution is a training facility and House of Formation under the auspices of the Southern African Catholic Bishops' Conference (SACBC).
St John Vianney was opened on 14 April 1948, by Archbishop Martin Lucas SVD, initially it was housed in temporary quarters at Queenstown prior to the completion of constructing the seminary in Waterkloof, Pretoria.
In 1950 the seminary moved to Pretoria, it was officially opened in March 1951 and staffed by Irish Franciscans.
In the climate of apartheid, St. Vianney initially catered for white South Africans, where as another seminary was set up St Peter's Seminary in Pevensey, KwaZulu-Natal, then in Hammanskraal and later in Garsfontein, to train indigenous priests so catered for the black Africans,[1] and from 1956 administered by the Dominican Order.
In 1999 the Higher Diploma in Ministry, which had been introduced a year earlier by Rector Dlungwane, was validated by the South African Qualifications Authority.