St Margaret was a parish in the ancient borough of Southwark, located south of the River Thames in the Brixton Hundred of Surrey.
[2] The parish was abolished in 1541 during the Dissolution of the Monasteries when the Priory of St Mary Overie was dissolved.
[3][4][5] The parish was unusual in that from 1444 its affairs were under the control of the Guild of the Assumption of St Margaret's Church.
In 1536 the church wardens obtained authority by act of Parliament for the purposes of enlarging the churchyard.
After being deconsecrated it was converted for use as the Borough Compter and destroyed in the Great Fire of Southwark in 1676.