The church shares a spire[1] with Holy Cross Anglican congregation is a major landmark in North Canberra, at the intersection of the four suburbs of Watson, Dickson, Downer and Hackett.

[5] Services were initially held in school rooms until the completion and official dedication of the church building on 16 December 1967.

[6] It faces the Signadou Canberra Campus of the Australian Catholic University, built in 1963 as the Dominican Sisters' Teacher Training College, across Antill Street.

The church is home to Meg's Toybox,[7][8] the major toy library for North Canberra, and the Stepping Stones for Life disability support organisation.

[9] Worship at St Margaret's is in the liberal Protestant tradition of the Uniting Church in Australia.