[1] In 1936, Father Wilfred Musgrave, Parish Priest of Ss Michael and Martin's Church, suggested that a mixed Catholic secondary school should be built in Hounslow.

His plan was suspended by the outbreak of the Second World War, but in 1952, a site was purchased at 106 Bath Road with a house, land, and an orchard.

[2] The school, initially called Archbishop Myers Secondary, received its first 279 pupils on 10 May 1960, welcomed by Headteacher Patrick Boland and 11 staff.

Originally six forms of entry were planned with a split site – a senior school located at the other end of Hounslow High Street.

These plans were dropped and in 1978 the buildings of the old Ss Michael and Martin's Primary School were included in the enlarged St Mark's site.