Tracing its roots back to 1904, it was the only Catholic further education provision in the region of Teesside for over 50 years.

Its buildings, staff and educational provision were merged with the other schools to form Trinity Catholic College, Middlesbrough.

[citation needed] In 1968, Middlesbrough Education Committee changed its admissions policy and it became a sixth form college in 1974, also known then as a senior high school.

[5] This, along with falling student numbers due to competition from the upgraded Middlesbrough College, meant the decision was made for the school to close in the summer of 2011.

[7] The refurbished St Mary's building continued to accommodate Trinity Sixth Form until 2019, when the decision was taken to vacate the site entirely and relocate the sixth form to a brand-new centre on the school's multi-million pound Lacy Road campus.