Severely damaged just 33 years later during the Great Fire of London in 1666, it was rebuilt once more by the office of Sir Christopher Wren.

Unlike most of Wren's City churches, St Mary Aldermary was reconstructed in the Gothic Revival style.

The main church space acts a public cafe during weekday business hours, with religious and meditative sessions held during mornings and evenings.

[8] St Mary Aldermary was badly damaged in the Great Fire of London of 1666,[9] although parts of its walls and tower survived.

[11] A legacy of £5,000 had been left by one Henry Rogers for the rebuilding of a church, and his widow agreed to use it to fund the reconstruction of St Mary's.

The tower is divided into storeys by string courses; the corners lead up to octagonal turrets, terminating in what George Godwin called "carved finials of impure design".

In 1876–7 major changes were made to the interior: an oak screen was inserted, dividing the lobby from the church; the pews and stalls were replaced, the organ was moved from the western gallery to the chancel; the floor was repaved, new stained glass put into the windows, and a new reredos installed.

[12] The latest interior restoration was finished in April 2005, with attention paid to the plaster ceilings and memorials on the north wall.

[18] In January 2010, the Bishop and Archdeacon of London invited the Moot Community to make their home in St Mary Aldermary.

Members committed to living a "rhythm of life", encompassing spiritual practices such as prayer, meditation and presence, and values such as acceptance, balance, creativity and hospitality.