St Paul's College is a Catholic primary and secondary school founded in 1958, located in Gilles Plains, in the north-eastern suburbs of Adelaide, South Australia.

Enrolments later surged after private and Housing Trust development occurred in the area, namely in the suburbs of Valley View, Ingle Farm, Modbury, Dernancourt and Surrey Downs.

After the restructuring of Christian Brothers' organisations in October 2007, the school is now a member of Edmund Rice Education Australia.

In 1997, the senior school as a distinct structure was established, with vertically-structured cross-year homegroups being created, along with the new house system.

In 2007, the partnership with Kildare College was rekindled, with students completing Year 11 & 12 SACE specialist subjects studying between the two campuses.