[4] According to the Toronto Star, Caitlin was "arguably its most popular character, whose storylines included her questioning her sexuality, an epilepsy diagnosis and the trauma after an ex committed suicide".
[5] In 1992, Mistysyn appeared as Caitlin at Degrassi High's television movie finale, School's Out!, where she uttered the quote "You were fucking Tessa Campanelli?
[8][9] American filmmaker Kevin Smith, a fan of the Degrassi series and of Mistysyn, wanted her to appear in 1995's Mallrats, but Universal Pictures insisted he use a better-known actress; the role Smith wanted for Mistysyn was instead given to Shannen Doherty,[10] who is seen wearing a Degrassi jacket in the film.
[12] Mistysyn is close friends with Degrassi co-star Amanda Stepto, and in the late 2000s the two had plans to develop their own comedy series, OverXposed, which did not come to fruition.
[5][16] In 1989, Mistysyn won a Gemini Award for Best Actress in a Continuing Leading Dramatic Role for Degrassi Junior High.
[12] In an online article for Medium, she revealed that she struggled with an eating disorder and anxiety near the end of Degrassi's run.