[4] Stacy Layne Matthews won the Snatch Game challenge for her impersonation of Mo'Nique as her character in the film Precious (2009),[5][6] and eliminated India Ferrah from the competition after winning a lip sync to "Meeting in the Ladies Room" (1985) by Klymaxx.

[7] Stacy Layne Matthews was eliminated on the seventh episode,[8] after placing in the bottom two of the design challenge, and losing a lip sync against Alexis Mateo.

[9][10][11] Stacy Layne Matthews is referenced in the song "Heather", a parody of Mariah Carey's "We Belong Together" (2005), by The AAA Girls, a supergroup with Drag Race contestants Alaska Thunderfuck, Courtney Act, and Willam Belli.

"Heather" was released as a single for Access All Areas in 2017 and received a music video, in which Stacy Layne Matthews made a cameo appearance.

[12] Stacy Layne Matthews made multiple appearances on season 4 (2018–2019) of the spin-off series RuPaul's Drag Race All Stars,[13] during the "Super Girl Groups, Henny!"

[14] Sam Damshenas of Gay Times has said Stacy Layne Matthews is "one of the most beloved" contestants in the Drag Race franchise.