In 1511 he was awarded the right to live outside the monastery and moved to Szydłowiec to work for the town's owner, Krzysztof Szydłowiecki, castellan of Sandomierz,[2] who was widely known as a patron of arts.

[8] Stanisław Samostrzelnik is best known for his ornate miniature paintings in a genealogical book of the Szydłowiecki family ("Liber genesos illustris Familiae Shidlovicae").

Upon his return he established his own workshop in Kraków[2] at Świdniecka Street, where he received commissions from the local patriciate, clergy and the royal court (including the Prayer Book of Queen Bona Sforza).

[6] Samostrzelnik decorated the prayer book of Princess Jadwiga Jagiellon (1535), a document of peace treaty with Ottoman Empire (1533), and the banner for Albrecht Hohenzollern.

[4][failed verification – see discussion] A characteristic feature of Samostrzelnik's miniatures is live, often contrasting color and Renaissance style referring to the Gothic tradition.

[2] In addition to the Danube school influences, the Dutch patterns and indirect connections with the Italian painting (ornamental and heraldic motifs, acquired during his stay in Hungary in 1514)[10] are visible in his work.