O'Toole has produced works for the top studios in the world including, Columbia, Paramount, Warner Bros., MGM, Universal, and 20th Century Fox.

Stanley O'Toole entered the film industry, accidentally, in 1959, as a payroll clerk for the Rank Organisation.

Directed by Lewis Gilbert, it was shot mostly on location in Prague[5] and was based on the true story of the assassination of Reinhard Heydrich.

It was on this project that Stanley first met Franklin J. Schaffner, whom he would go on to work with on three other films, including The Boys from Brazil and Sphinx.

[10] Schaffner's The Boys from Brazil, released in 1978, based on Ira Levin's best-selling novel, starred Sir Laurence Olivier, Gregory Peck and James Mason.

[12] Remembering their partnership on The Boys from Brazil and the aborted Entebbe project, Franklin J. Schaffner and Stanley O'Toole bought the rights to Robin Cook's The Sphinx.

[14][15] Sphinx was not received well by critics, however, but made its budget back and was the number one film in Japan, the second largest market in the world at the time.

[19] During his time at Village Roadshow, Stanley oversaw the production of numerous films, including The Delinquents, Quigley Down Under, Hurricane Smith, Bloodmoon and Dead Sleep.

Films made during this time include The Secret Garden, Executive Decision and preparation of Andrew Lloyd Webber's The Phantom of the Opera.