[1] Stanton Hall occupies an entire 2-acre (0.81 ha) city block north of downtown Natchez, bounded by High, Commerce, Monroe, and Pearl Streets.

Its front entrance features a two-story Greek temple portico, with four fluted cast-iron Corinthian columns supporting an entablature and gabled pediment.

The interior is elaborately decorated, using materials such as imported Italian marble, textiles from Paris and chandeliers made of glass and bronze.

In 1940 it was acquired by the Pilgrimage Garden Club,[4] which uses it as its headquarters and operates it as a museum and event venue.

The house's insides have appeared in ABC's mini-series North and South as the Mains' mansion interiors.