It survived the Great Fire of London, was extensively damaged by a Nazi German Luftwaffe aerial bomb in 1944 but was subsequently restored.
It has a distinctive timber-framed façade, cruck roof and an internal courtyard.
The historic interiors include a great hall, used by the Institute and Faculty of Actuaries.
The ground-floor street frontage is let to shops and restaurants, required to use plainer signage than they do on less sensitive buildings.
For a time, the building appeared on the packaging of Old Holborn tobacco.