StarTalk is a podcast on science, comedy, and popular culture hosted by astrophysicist Neil deGrasse Tyson and comedian Chuck Nice, with various other comic and celebrity co-hosts and frequent guests from the worlds of science and entertainment.

[1] Past co-hosts have included Colin Jost, Lynne Koplitz, Leighann Lord, Eugene Mirman, John Oliver, and Kristen Schaal.

[2] Guests have included astronaut Buzz Aldrin, actor Morgan Freeman, George Takei, comedian Joan Rivers, Arianna Huffington, YouTuber Sam Denby, Richard Dawkins and writer Mary Roach.

StarTalk has a segment called Cosmic Queries, in which listeners send in questions about the universe to be answered on the show.

It is hosted by Gary O'Reilly and frequent StarTalk co-host Chuck Nice.