StarTalk is a podcast on science, comedy, and popular culture hosted by astrophysicist Neil deGrasse Tyson and comedian Chuck Nice, with various other comic and celebrity co-hosts and frequent guests from the worlds of science and entertainment.

[1] Past co-hosts have included Colin Jost, Lynne Koplitz, Leighann Lord, Eugene Mirman, John Oliver, and Kristen Schaal.

[2] Guests have included astronaut Buzz Aldrin, actor Morgan Freeman, George Takei, comedian Joan Rivers, Arianna Huffington, YouTuber Sam Denby, Richard Dawkins and writer Mary Roach.

StarTalk has a segment called Cosmic Queries, in which listeners send in questions about the universe to be answered on the show.

In May 2014, Rolling Stone ranked StarTalk at number 13 on its list of "The 20 Best Comedy Podcasts Right Now".