State Trooper takes place in Las Vegas, Reno, and Carson City, Nevada, but was filmed by Revue Studios at Iverson Movie Ranch in Chatsworth in Los Angeles County in California.

Its fictional stories focus upon miners, ranchers, dude ranches, released convicts, and murder mysteries, often with surprise endings.

Robert Armstrong appeared in 24 episodes as Sheriff Andy Anderson, who developed a good working relationship with Cameron's character, Blake.

Tom Greenway appeared in four episodes as Sheriff Bronson: "Stay Lost, Little Girl", "Dangerous Honeymoon", "Full Circle", and "Death on Wheels".

Originally conceived to compete with Highway Patrol,[2] the show pilot was an episode of the anthology series Star Stage,[3] released in February 1956 and titled "Killer on Horseback".