Programs in the liberal arts and sciences and professional studies lead to bachelor's and associate degrees.

The master's degree is awarded in 13 professional and liberal arts and sciences fields of study.

The college participates in doctoral programs of the CUNY Graduate Center in biochemistry, biology, chemistry, computer science, nursing, physics, and psychology.

[10] The CSI Library supports the research needs of its students, faculty, and staff by collecting, preserving, and providing access to scholarly resources in a variety of formats.

[13] As of the 2016 school year, U.S. News & World Report has ranked The College of Staten Island between 146th and 187th in their Best Regional Universities in the North category, and tied for 118th in Best Undergraduate Engineering Programs that do not offer a doctorate, yet the college is unranked nationally.

The university was a provisional member of the National Collegiate Athletic Association (NCAA) Division II, but joined the East Coast Conference (ECC) in the 2020–21 academic year.

Men's sports are baseball, basketball, cross country, soccer, swimming and diving, tennis, and track and field (indoor and outdoor); women's sports are basketball, cross country, soccer, softball, swimming and diving, tennis, and track and field (indoor and outdoor).