During the 2012–13 Serie A season, Beltrame also began to earn a handful of first-team call-ups by head coach, Antonio Conte.

[3] He made his debut for Juventus on 26 January 2013 against Genoa, coming on as an 82nd-minute substitute for Claudio Marchisio, as the club was searching for a win during a 1–1 draw.

[8] However, in winter transfer window of 2015, Beltrame returned to Juventus for €1 million in a 4+1⁄2-year contract, with Jakub Hromada and Atila Varga moved to Sampdoria for €600,000 and €400,000 respectively.

[11] On 27 January 2020, Beltrame signed a permanent deal with Bulgarian club CSKA Sofia, earning a reported €1.5 million per year.

He made his official debut on 15 February 2020 in the Eternal Derby against Levski Sofia, starting from the first minute and being substituted 10-minutes before the end.

[14] At the end of the 2022–23 season, following Marítimo's relegation to the Liga Portugal 2, Beltrame's contract expired and he left the Funchal-based side.