Mireșu Mare (Hungarian: Nagynyíres) is a commune in Maramureș County, northwestern Romania.

It is located near Ulmeni, on the right, eastern bank of the river Someș.

The commune is composed of seven villages: Dăneștii Chioarului (Dánfalva), Iadăra (Jeder), Lucăcești (Szamoslukácsi), Mireșu Mare, Remeți pe Someș (Gyökeres), Stejera (Jávorfalu), and Tulghieș (Szamostölgyes).

The commune belongs to the Baia Mare metropolitan area.

This Maramureș County location article is a stub.