The first novel in her Saz Martin series, Calendar Girl, was voted fifth equal in the 2007 international poll "The Big Gay Read".

[10] Duffy has written many plays, including The Book of Ruth (and Naomi) for the Bush Theatre's inaugural Sixty Six Books set of plays, an adaptation of Medea, Prime Resident, Immaculate Conceit, The Hand, and solo shows Breaststrokes and The Tedious Predictability of Falling in Love.

She has performed her solo show Breaststrokes (Time Out and The Guardian Critic's Choice) in London, Belfast, Cardiff, Dublin, York, and Amsterdam.

Ordinary Darkness at Hen and Chickens – all for Shaky Isles; and The Seduction of Ms Sarah Hart (Caron Pascoe) at The Oval for Kindred Spirits.

[citation needed] On screen, she appeared in a 1997 episode of ITV police procedural series The Bill[12] the 2001 movie Absolution.

[14] Duffy was appointed Officer of the Order of the British Empire (OBE) in the 2016 Birthday Honours for services to the arts.