Quimbo was born on November 23, 1969, to food scientist Estrella Alabastro, who would serve as dean of the College of Home Economics at the University of the Philippines Diliman and as a secretary of science and technology under the Arroyo administration.

[4] From 2011 to 2013, Quimbo served in the rank of full professor into the Prince Clause Professorial Chair at the Erasmus University Rotterdam in the Netherlands.

[5] Quimbo's research portfolio focuses on the field of health economics, industrial organization, microeconomics, education, poverty, and public policy.

[10] In the May 9, 2019, election, Quimbo easily won the seat, defeating former representative Eugene de Vera and independent Mauro Arce.

In the 18th Congress, Quimbo was a member of a technical working group tasked to study the franchise renewal of ABS-CBN, the largest broadcaster in the Philippines.

She was the lone dissenter against the decision of two other members, representatives Pablo John Garcia and Xavier Jesus Romuald, to disapprove the application of ABS-CBN for another franchise.

[23] On January 13, 2025, Quimbo was appointed as acting chairperson of the House Committee on Appropriations after Representative Elizaldy Co stepped down from the post due to health concerns.

Prior to the 2024 State of the Nation Address on July 22, 2024, Miro confirmed that Quimbo will run for mayor of Marikina in the 2025 local elections and thus will not seek another term as representative.