[2][3] She is a senior research scientist at the Computer Science and Artificial Intelligence Laboratory (CSAIL) of the Massachusetts Institute of Technology (MIT).

In 2011, she began publishing controversial papers in low-impact, open access journals on biology and medical topics; the articles have received "heated objections from experts in almost every field she's delved into," according to the food columnist Ari LeVaux.

[4] Seneff attended the Massachusetts Institute of Technology (MIT), earning her Bachelor of Science (BS) in biophysics in 1968, master's (MS) and engineering (E.E.)

She was elected a Fellow of the International Speech Communication Association (ISCA) in 2012 as recognition for her "contributions to conversational human-computer systems and computer-assisted language learning".

[4][10] According to the food columnist A. LeVaux, Seneff's work in this area has made her "a controversial figure in the scientific community" and she has received "heated objections from experts in most every field she's delved into".

[12] Jerry Steiner, the executive vice president of sustainability at Monsanto, said in an interview regarding the study that "We are very confident in the long track record that glyphosate has.

In 2022, she co-authored the article "Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs"[15] in the peer-reviewed journal Food and Chemical Toxicology with Peter A. McCullough, a cardiologist known for spreading disinformation during the pandemic.