Stephen of Simmern-Zweibrücken (German: Stefan Pfalzgraf von Simmern-Zweibrücken) (23 June 1385 – 14 February 1459, Simmern) was Count Palatine of Simmern and Zweibrücken from 1410 until his death in 1459.

[1] He was the son of King Rupert of Germany and his wife Elisabeth of Nuremberg.

In June of 1410, Stephen married Anna of Veldenz, who died in 1439.

In 1448 he succeeded to one part of Palatinate-Neumarkt and sold the other to his younger brother Otto[citation needed].

Stefan of Simmern-Zweibrücken and Anna of Veldenz had issue: This article about a member of the German nobility is a stub.