His father, who had come to England from France following the revocation of the Edict of Nantes, died soon afterwards and he was brought up by his uncle, Captain Peter Demainbray (d. 1733) who placed him at Westminster School.
The 1745 Jacobite Rising brought him to take arms for the government for four years, and he was a volunteer at the Battle of Prestonpans.
[4] His assistant there was James Stephen Rigaud, who married Demainbray's daughter Mary in Richmond in 1771.
In London on 22 February 1726, in a clandestine marriage, Demainbray married his first wife, Mary Worsham (d. 1755 Montpellier, France) and they had five children.
In 1755 he married, at St Anne's Church, Soho, his second wife, Sarah Horne (a sister of John Horne Tooke), and fathered a further four children including Stephen George Francis Triboudet Demainbray.