He is best known for his posthumous guest appearance on Lil Wayne's 2008 single "Lollipop", which peaked atop the Billboard Hot 100 and received diamond certification by the Recording Industry Association of America (RIAA).

The former group signed with Def Jam Recordings and became best known for their 1998 single "Cheers 2 U", which entered the top 40 of the Billboard Hot 100 and preceded the release of their sole studio album (1998).

He made a breakthrough working with R&B singer Ginuwine, writing and co-producing the 1996 song "Pony" which became a major hit and a milestone in both Garrett and Timbaland's careers.

After working with Ginuwine, Garrett assisted in producing songs for Nicole Wray for her 1998 debut album, Make It Hot.

Garrett died at age 33 at the Baptist Hospital East in Louisville, Kentucky, on February 25, 2008, from complications of a medical procedure.

According to the Jefferson County Coroner's Office, he went into respiratory arrest and bled to death after the removal of a catheter that was improperly inserted into his neck.

In 2020, Garrett was featured alongside Bryson Tiller on Jack Harlow's "Luv Is Dro", from his debut album Thats What They All Say.