Henderson is the host of Detroit Today, a weekday talk show that features conversations about inequality of all kinds, democratic and civic participation and great ideas from contemporary books.

[7] Henderson has worked for the Baltimore Sun, the Chicago Tribune, the Lexington Herald-Leader, and Knight Ridder as a reporter, editorial writer and editor.

In 2016, Henderson wrote that Michiganders should take legislators who took money to shield Michigan's charter schools from oversight, "sew them into burlap sacks with rabid animals, and toss them into the Straits of Mackinac".

[8][16] In response to his firing, Henderson said on his own radio show that he apologized to the women involved and said it was "bad judgement" on his part, but he also said that he disagreed with the decision by the Free Press and would be "exploring legal action.

[17] In November 18, 2024, Henderson announced his departure from Detroit public radio, ending his show “Created Equal" due to station “disinvestment.