Stephen Mattoon (May 5, 1816 – 1889) was an American Presbyterian missionary who worked in Siam from 1847 to 1864.

Mattoon served as a translator for Townsend Harris in spring 1856.

[2] After returning to the U.S., Mattoon was appointed in 1870 as the first President of Johnson C. Smith University, which was known as the Biddle Memorial Institute in 1870 and then as Biddle University during his tenure as president, till 1884.

[3] Mattoon's grandson Norman Thomas was the Socialist Party candidate for President six times.

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