After college, Giatzoglou began his professional club career in Lebanon.

Giatzoglou's pro career was mainly noted for his successes with the Greek Basket League club Olympiacos Piraeus.

Giatzoglou played in three FIBA EuroBasket tournaments with Greece's national team.

In 2014, Giatzoglou was hired as an assistant coach to work in South Korea, with the Goyang Orions of the Korean Basketball League.

[5][6] In October 2016, Giatzoglou endorsed the Neo-Nazi[8] political party Golden Dawn, and attended the celebration of their newspaper's 1,000th issue.