The 110th congressional delegation from the U.S. state of Minnesota had three Republicans and five Democratic-Farmer-Labor Party members (DFLers).

Results of the 2008 United States House of Representatives elections in Minnesota by district: Tim Walz Democratic (DFL) Tim Walz Democratic (DFL) This district extended across southern Minnesota from the border with South Dakota to the border of Wisconsin.

[2] Walz, a former teacher and Command Sergeant Major in the National Guard[3] had no opponent in the race for the DFL nomination for the seat in the September 12, 2008 primary election.

[13] John Kline Republican John Kline Republican This district spans the width of the entire southern metro area and contains all of Carver, Scott, Le Sueur, Goodhue and Rice Counties and most of Dakota County.

[2] Republican John Kline held on to the second district seat in 2006, defeating DFL challenger, former FBI agent, Coleen Rowley.

The district Republican lean, Kline's unwavering support for Bush and the Iraq War did not make him appear too vulnerable to a challenger in 2008.

[15] On October 4, 2007, Iraq War veteran Steve Sarvi announced he would challenge Kline for the seat.

Incumbent Republican Jim Ramstad, who had represented the district since 1991, announced on September 17, 2007, that he would not seek re-election in 2008.

[13] Keith Ellison Democratic (DFL) Keith Ellison Democratic (DFL) This district covers eastern Hennepin County, including the entire city of Minneapolis, Minnesota, along with parts of Anoka and Ramsey counties.

[2] Bachmann won a hard-fought battle against Patty Wetterling in 2006, with the help of Karl Rove and Dick Cheney campaigning on her behalf[39] and a multimillion-dollar warchest.

[13] Collin Peterson Democratic (DFL) Collin Peterson Democratic (DFL) This district covers almost all of the western side of Minnesota from the Canada–US border down to Lincoln County and is the largest district in the state.

[2] As chairman of the House Agriculture Committee, 9-term DFLer Collin Peterson is at home in this mostly-agricultural district.

The district leaned Democratic owing to the loyalty of miners, loggers, and farmers to the DFL.