Substance Abuse is a Los Angeles based hip-hop group consisting of the duo Subz (Justin Hollingsworth) and Eso Tre (John Heath).
in 2000 on the now defunct Ground Control Records, which was followed by the single "Can't Call It"/"No Guarantees" featuring P.E.A.C.E.
Their debut album, Overproof, was released in 2006, and features cameos from Kool Keith, MF Doom, Motion Man, Saafir, and Rasco.
The album received four stars in URB and Scratch Magazine.
The group released their sophomore effort, Background Music, featuring Tash, MC Eiht, KRS-One, Sadat X, Percee P, Myka 9, and Max Julien in 2013.